EXPLORING THE THERAPEUTIC POTENTIAL OF METHANOL LEAF EXTRACT FROM Ziziphus mauritiana L. : A CANDIDATE FOR TRADITIONAL MEDICINE
Keywords:
Ziziphus mauritiana L., Methanol Extract, Traditional Medicine Candidate, Phytochemical Screening, GC-MS AnalysisAbstract
The tropical herbaceous plant known as bidara (Ziziphus mauritiana L.) offers a number of health advantages. Bidara leaves are traditionally used in Indonesia, particularly in Aceh, to treat a variety of illnesses. Considering its potential health benefits, this research aims to examine the potential of methanol extract of bidara leaves as a candidate for traditional medicine. This research focuses on the results of screening for phytochemical activity in the methanol extract of bidara leaves and the results of GC-MS analysis of secondary metabolites in the methanol extract of bidara leaves as potential candidates for traditional medicine. This research is expected to be able to identify the compounds contained in bidara leaves as a whole and find out the results of identifying secondary metabolites that have the potential to be candidates for traditional medicine. This study used qualitative descriptive methods for phytochemical screening and GC-MS analysis. Bidara leaf extract was obtained by methanol extraction, and its concentration of secondary metabolites, including alkaloids, flavonoids, saponins, tannins, and terpenoids, was then determined by testing the extract with a number of reagents. To determine the chemical structures of the extract's constituents, GC-MS analysis was performed. The findings demonstrated the presence of several secondary metabolites, including alkaloids, steroids, saponins, flavonoids, and phenolics, in the methanol extract of bidara leaves. Several active substances with potential applications in traditional medicine were found through GC-MS analysis. These compounds have various health benefits including anti-inflammatory, antioxidant, and antimicrobial. This research succeeded in identifying active compounds in the methanol extract of bidara leaves which have potential as candidates for traditional medicine. The results of phytochemical screening and GC-MS analysis show that bidara leaves can be further developed as an effective and safe raw material for traditional medicine.
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